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Blood-brain barrier research group
Our research focus is on understanding the temporal gate separating the body from the brain
Welcome to Zhang Lab! We study the blood-brain barrier (BBB), a structure that both protects delicate neurons from environmental toxins yet also allows transport of nutrients. A molecular clock within this gateway to the brain makes it highly dynamic over the course of the day:night cycle. Our work seeks to understand how the clock influences the BBB, what molecules are gated by time, and how this process might be changed by disease.
Jan 2023 eLife publication "Ecdysone acts through cortex glia to regulate sleep in Drosophila"
Sept 2021 Zhang lab starts at Emory University
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